Folates in human serum

Serum folates in young dairy heifers.

1. In the first trial, hourly blood samples were drawn during the light period (06.30-20.30 hours) from thirty-four dairy heifers in two groups of different ages. 2. Concentrations of serum folates were 8.2 (SE 0.1) ng/ml at the age of 18.2 (SE 0.6) d and 14.8 (SE 0.2) ng/ml at 120.7 (SE 2.9) d (P less than or equal to 0.001). 3. In the second trial, forty heifers were randomly assigned to a fa...

Serum and erythrocyte folates in combined iron and folate deficiency.

A high incidence of iron and folate deficiency was found in 80 female subjects living in a private institution. Iron therapy in individuals with low serum iron values resulted in a significant increase in hemoglobin levels. An improvement in serum and RBC folate levels was also found following iron therapy but this could not be attributed to treatment since a similar increase was observed in un...

New evidence for a binding principle specific for folates as a normal constituent of human serum.

The binding of folate by human serum was investigated by incubating serum with [3H] pteroylglutamic acid followed by charcoal separation of free and bound fractions. Sera from all of 99 normal volunteers and 9 16 patientsexhibitedsome degree of folate binding, ranging from less than 0. 1 to greater than 8 ng/ml. This binding phenomenon was found, by competitive inhibition, to be specific for fo...

Serum and red cell folates, and serum vitamin B 12 in protein calorie malnutrition.

Serum folates in gestating swine after folic acid addition to diet.

Folic acid was added to the diet as a simple means to increase serum folates in gestating sows. At weaning, 95 multiparous sows were randomly assigned to five treatments. Of these sows, 67 farrowed and were used for this trial. Three supplementation levels of folic acid added to a commercial diet at 3, 9 and 27 mg per kg were studied. A commercial diet without any supplementation of folic acid ...